Cisco ISE vulnerabilities: known CVEs & security history
Cisco · Network / Security · 14 tracked CVEs · 1 actively exploited · updated September 2026 · what is a CVE? →
This is the full list of known vulnerabilities (CVEs) across all Cisco ISE release lines — 14 in total, with 1 actively exploited in the wild. A CVE here doesn't mean your version is affected — check Cisco ISE's current status and the safe version to run.
Known Cisco ISE CVEs
Actively-exploited and most-severe first. Open any CVE for full details.
| CVE | Severity | CVSS | EPSS | Year |
|---|---|---|---|---|
| CVE-2021-44228⚡ exploited | critical | 10 | 100% | 2021 |
| CVE-2026-20186 | critical | 9.9 | 6% | 2026 |
| CVE-2026-20180 | critical | 9.9 | 6% | 2026 |
| CVE-2026-20147 | critical | 9.9 | 11% | 2026 |
| CVE-2026-20181 | critical | 9.1 | 1% | 2026 |
| CVE-2026-20190 | high | 7.5 | 0% | 2026 |
| CVE-2026-20136 | medium | 6 | 1% | 2026 |
| CVE-2026-20146 | medium | 5.5 | 0% | 2026 |
| CVE-2026-20195 | medium | 5.3 | 0% | 2026 |
| CVE-2026-20148 | medium | 4.9 | 9% | 2026 |
| CVE-2026-20132 | medium | 4.8 | 0% | 2026 |
| CVE-2025-20205 | medium | 4.8 | 0% | 2025 |
| CVE-2025-20204 | medium | 4.8 | 0% | 2025 |
| CVE-2026-20193 | medium | 4.3 | 0% | 2026 |
Is my Cisco ISE version affected?
The list above spans every release. To know whether your version is affected — and the minimum safe version to upgrade to — check it directly.
Check your Cisco ISE version → · Monitor Cisco ISE for new CVEs →
Cisco ISE vulnerabilities — frequently asked
How many known vulnerabilities does Cisco ISE have?
IsItPatched tracks 14 CVEs for Cisco ISE, 1 of which is actively exploited (CISA KEV). 5 are critical-severity and 1 high-severity. These span every release line — what matters is whether the version you run is affected.
Does Cisco ISE have any actively-exploited vulnerabilities?
Yes — 1 Cisco ISE CVE is in CISA's Known Exploited Vulnerabilities catalog, meaning it is confirmed exploited in the wild (1 linked to ransomware). Patch it as a priority.
What is the most severe Cisco ISE vulnerability?
Among tracked issues, CVE-2021-44228 (CRITICAL, CVSS 10), which is actively exploited, ranks highest — a Improper input validation weakness.
Is Cisco ISE safe to use?
It depends on the version. The latest supported Cisco ISE release clears the known issues; older versions may still be affected. Check the exact version you run for a verdict.
CVE data aggregated from NVD, CISA KEV and EPSS (FIRST.org). Related: Cisco ISE security status · Cisco ISE end-of-life · actively-exploited CVEs. Always verify against Cisco's advisories — see our disclaimer.