Cisco ISE vulnerabilities: known CVEs & security history
Cisco · Network / Security · 43 tracked CVEs · 2 actively exploited · updated October 2026 · what is a CVE? →
This is the full list of known vulnerabilities (CVEs) across all Cisco ISE release lines — 43 in total, with 2 actively exploited in the wild. A CVE here doesn't mean your version is affected — check Cisco ISE's current status and the safe version to run.
Known Cisco ISE CVEs
Actively-exploited and most-severe first. Open any CVE for full details.
| CVE | Severity | CVSS | EPSS | Year |
|---|---|---|---|---|
| CVE-2026-76460⚡ exploited | critical | 10 | 14% | 2026 |
| CVE-2021-44228⚡ exploited | critical | 10 | 100% | 2021 |
| CVE-2026-20192 | critical | 10 | — | 2026 |
| CVE-2026-20130 | critical | 10 | — | 2026 |
| CVE-2026-20234 | critical | 9.9 | — | 2026 |
| CVE-2026-20186 | critical | 9.9 | 6% | 2026 |
| CVE-2026-20180 | critical | 9.9 | 6% | 2026 |
| CVE-2026-20147 | critical | 9.9 | 10% | 2026 |
| CVE-2026-20181 | critical | 9.1 | 9% | 2026 |
| CVE-2025-20343 | high | 8.6 | 1% | 2025 |
| CVE-2026-76425 | high | 7.6 | — | 2026 |
| CVE-2026-20190 | high | 7.5 | 1% | 2026 |
| CVE-2026-76424 | high | 7.2 | — | 2026 |
| CVE-2026-20136 | medium | 6 | 0% | 2026 |
| CVE-2023-20193 | medium | 6 | 0% | 2023 |
| CVE-2026-20146 | medium | 5.5 | 0% | 2026 |
| CVE-2025-20304 | medium | 5.4 | 0% | 2025 |
| CVE-2025-20303 | medium | 5.4 | 4% | 2025 |
| CVE-2026-76447 | medium | 5.3 | — | 2026 |
| CVE-2026-76444 | medium | 5.3 | — | 2026 |
| CVE-2026-76439 | medium | 5.3 | — | 2026 |
| CVE-2026-76433 | medium | 5.3 | — | 2026 |
| CVE-2026-20195 | medium | 5.3 | 0% | 2026 |
| CVE-2026-76451 | medium | 4.9 | — | 2026 |
| CVE-2026-76450 | medium | 4.9 | — | 2026 |
| CVE-2026-76449 | medium | 4.9 | — | 2026 |
| CVE-2026-76448 | medium | 4.9 | — | 2026 |
| CVE-2026-76446 | medium | 4.9 | — | 2026 |
| CVE-2026-76434 | medium | 4.9 | — | 2026 |
| CVE-2026-76432 | medium | 4.9 | — | 2026 |
| CVE-2026-76431 | medium | 4.9 | — | 2026 |
| CVE-2026-76428 | medium | 4.9 | — | 2026 |
| CVE-2026-76427 | medium | 4.9 | — | 2026 |
| CVE-2026-76426 | medium | 4.9 | — | 2026 |
| CVE-2026-20148 | medium | 4.9 | 7% | 2026 |
| CVE-2025-20131 | medium | 4.9 | 0% | 2025 |
| CVE-2026-20132 | medium | 4.8 | 0% | 2026 |
| CVE-2025-20289 | medium | 4.8 | 0% | 2025 |
| CVE-2025-20205 | medium | 4.8 | 0% | 2025 |
| CVE-2025-20204 | medium | 4.8 | 0% | 2025 |
| CVE-2024-20479 | medium | 4.8 | 0% | 2024 |
| CVE-2026-20193 | medium | 4.3 | 0% | 2026 |
| CVE-2025-20305 | medium | 4.3 | 0% | 2025 |
Is my Cisco ISE version affected?
The list above spans every release. To know whether your version is affected — and the minimum safe version to upgrade to — check it directly.
Check your Cisco ISE version → · Monitor Cisco ISE for new CVEs →
Cisco ISE vulnerabilities — frequently asked
How many known vulnerabilities does Cisco ISE have?
IsItPatched tracks 43 CVEs for Cisco ISE, 2 of which are actively exploited (CISA KEV). 9 are critical-severity and 4 high-severity. These span every release line — what matters is whether the version you run is affected.
Does Cisco ISE have any actively-exploited vulnerabilities?
Yes — 2 Cisco ISE CVEs are in CISA's Known Exploited Vulnerabilities catalog, meaning they are confirmed exploited in the wild (1 linked to ransomware). Patch these as a priority.
What is the most severe Cisco ISE vulnerability?
Among tracked issues, CVE-2026-76460 (CRITICAL, CVSS 10), which is actively exploited, ranks highest — a CWE-648 weakness.
Is Cisco ISE safe to use?
It depends on the version. The latest supported Cisco ISE release clears the known issues; older versions may still be affected. Check the exact version you run for a verdict.
CVE data aggregated from NVD, CISA KEV and EPSS (FIRST.org). Related: Cisco ISE security status · Cisco ISE end-of-life · actively-exploited CVEs. Always verify against Cisco's advisories — see our disclaimer.